QUIZ: No. 8, 20/04/2025

USG

ANS – Zinners syndrome

Findings: Multiple cystic hyperintense structures lying close together, in the region of the left seminal vesicle – LEFT SEMINAL VESICLE CYST. Normal right kidney and absence of left kidney – LEFT RENAL AGENESIS. Obstruction of the ejaculatory duct with dilated tortuous vas deferens- LEFT EJACULATORY DUCT OBSTRUCTION. Hyperintense left remnant ureter draining into an ipsilateral seminal vesicle cyst - ATRETIC LEFT URETER

Zinner syndrome is a triad of Wolffian duct anomaly comprising unilateral renal agenesis, ipsilateral seminal vesicle cyst and ejaculatory duct obstruction. Maldevelopment of the Wolfian duct occurs before the 7th week when the ureteric bud forms from the distal portion. The seminal vesicle also originates from Wolfian duct under the effect of testosterone. Hence maldevelopment of Wolffian duct results in cystic seminal vesicle and ipsilateral renal agenesis. Seminal vesicle cysts of Zinner's syndrome derive from the remaining Wolfian duct and are usually larger, round, or tubulosaccular with irregular margins.

The female counterpart of Zinner syndrome is Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA) syndrome.